The 2021 Research, Invention and Innovation Conference was held for the second time, on September 1-2, 2021 via a Virtual conference. There were three main sessions with about 150 presented works, including the session of Innovative Materials Engineering (iME), Innovative Electricals and Electronics (iEE), and Innovative Sustainable Sciences (iSS). In this year, it was a great honor to have the keynote speakers from Professor Yang Zhigang from Tsinghua University, Professor San Hoa Thang from Monash University, Professor Yuttana Kumsuwan from Chiang Mai University, and especially we had a special talk from Dr.Wilaiporn Chetanachan from SCG who is the innovation business guru of Thailand.